ACTIVE GRANTS

Translating Metabolic Responses to Mechanical Insult into Early Interventions to Prevent PTOA PR172087
09/01/2018–08/31/2023 Total Project Costs: $9,999,762
Mitchell Coleman, PhD; PI: Joseph Buckwalter

Training Program in Free Radical and Radiation Biology
07/01/1999 – 07/31/2025 Total Project Costs: $93,000
Mitchell Coleman, PhD; PI: Douglas Spitz

Targeting Nitrate-Nitrite-NO pathway for Ameliorating Muscle and Bone Comorbidities in Duchenne Muscular Dystrophy
09/01/2018–08/31/2023 Total Project Costs: $1,642,613
Hongshuai Li, PhD, PI

The efficacy of matrix-bound nanovesicles in preventing post-trauma osteoarthritis (PTOA) & The efficacy of MBVs in alleviating muscle fibrosis of Duchenne muscular dystrophy (DMD)
04/05/2023 – no end date Total Project Costs: $0
Hongshuai Li, PhD, PI

Correlating PROMIS-29 with Weight-Bearing CT Following Tibial Plafond Fracture.
01/01/2021–12/31/2022 Total Project Costs: $23,937
J Lawrence Marsh, PhD, PI Justin Haller

3D Joint Space Width from Weight Bearing CT as an Imaging Biomarker of PTOA.
01/01/2021–12/31/2023  Total Project Costs: $928,248.73
J Lawrence Marsh, PhD, Co-PI

Translating Metabolic Responses to Mechanical Insult into Early Interventions to Prevent PTOA .
09/01/2018–08/31/2022  Total Project Costs: $9,999,762
J Lawrence Marsh, PhD, Project lead

Simulation to Support Competency-Based Training in Orthopedic Trauma.
09/30/2017–07/31/2022  Total Project Costs: $1,876,254
J Lawrence Marsh, PhD, PI: Thomas, Geb W./Anderson, Donald D.

CST6-mRNA activated matrices for efficient bone regeneration.
03/01/2022 – 02/29/2024  Total Project Costs: $424,875
James Martin, PhD, Co-Investigator. PI: Salem, Aliasger K.

Exosome-based Cell Homing and Lineage-Specific Differentiation Strategies for Dental Pulp Regeneration.
07/14/2021 – 06/30/2023  Total Project Costs: $303,484
James Martin, PhD, Co-Investigator. PI: Seol, Dong Rim

Anti-fibrotic Effect of Exosomes on Human TMJ Tissues: A Pilot Study.
07/01/2021 – 06/30/2023  Total Project Costs: $29,998
James Martin, PhD, Co-Investigator. PI: Shin, Kyungsup

A Novel Strategy of Endogenous Progenitor Cell Homing Using Exosomes for Condylar Fibrocartilage Repair in Temporomandibular Joint.
09/10/2020–08/31/2023  Total Project Costs: $305,917
James Martin, PhD, Co-Investigator. PI: Shin, Kyungsup

Translating Metabolic Responses to Mechanical Insult into Early Interventions to Prevent PTOA PR172087.
09/01/2018–08/31/2023  Total Project Costs: $9,999,762
James Martin, PhD, Project 1 Investigator. PI: Buckwalter, Joseph A.

Preventive and Therapeutic Effects of Bone Marrow Stem Cell-Derived Exosomes on Spine Dural Fibrosis.
05/10/2022 – 04/30/2024  Total Project Costs: $367,342
James Martin, PhD, Co-Investigator. PI: Seol, Dong Rim

Platelet Rich Plasma for Osteoarthritis: Role of Exosomes in Effectiveness (#967803).
05/01/2022 – 04/30/2024  Total Project Costs: $49,378
James Martin, PhD, Co-Investigator. PI: Duchman, Kyle R.

CST6-mRNA activated matrices for efficient bone regeneration.
03/01/2022 – 02/29/2024  Total Project Costs: $424,875
Dong Rim Seol, PhD, Co-Investigator. PI: Salem, Aliasger K.

Anti-fibrotic Effect of Exosomes on Human TMJ Tissues: A Pilot Study .
07/01/2021 – 06/30/2023  Total Project Costs: $29,998
Dong Rim Seol, PhD, Co-Investigator. PI: Shin, Kyungsup.

Exosome-based Cell Homing and Lineage-Specific Differentiation Strategies for Dental Pulp Regeneration.
07/14/2021 – 06/30/2024  Total Project Costs: $303,484
Dong Rim Seol, PhD, PI

A Novel Strategy of Endogenous Progenitor Cell Homing Using Exosomes for Condylar Fibrocartilage Repair in Temporomandibular Joint.
09/10/2020–08/31/2023  Total Project Costs: $305,917
Dong Rim Seol, PhD, Co-Investigator. PI: Shin, Kyungsup.

Translating Metabolic Responses to Mechanical Insult into Early Interventions to Prevent PTOA PR172087.
09/01/2018–08/31/2023  Total Project Costs: $9,999,762
Dong Rim Seol, PhD, Co-Investigator. PI: Buckwalter, Joseph A.

Preventive and Therapeutic Effects of Bone Marrow Stem Cell-Derived Exosomes on Spine Dural Fibrosis.
05/10/2022 – 04/30/2024  Total Project Costs: $367,342
Dong Rim Seol, PhD, PI